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Toxoplasma gondii Relies on Both Host and Parasite Isoprenoids and Can Be Rendered Sensitive to Atorvastatin

Intracellular pathogens have complex metabolic interactions with their host cells to ensure a steady supply of energy and anabolic building blocks for rapid growth. Here we use the obligate intracellular parasite Toxoplasma gondii to probe this interaction for isoprenoids, abundant lipidic compounds...

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Détails bibliographiques
Auteurs principaux: Li, Zhu-Hong, Ramakrishnan, Srinivasan, Striepen, Boris, Moreno, Silvia N. J.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798403/
https://ncbi.nlm.nih.gov/pubmed/24146616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003665
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