IMP Dehydrogenase from the Protozoan Parasite Toxoplasma gondii

The opportunistic apicomplexan parasite Toxoplasma gondii damages fetuses in utero and threatens immunocompromised individuals. The toxicity associated with standard antitoxoplasmal therapies, which target the folate pathway, underscores the importance of examining alternative pharmacological strate...

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Bibliographic Details
Main Authors: Sullivan, William J., Dixon, Stacy E., Li, Catherine, Striepen, Boris, Queener, Sherry F.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2005
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Mechanisms of Action: Physiological Effects
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1140536/
https://ncbi.nlm.nih.gov/pubmed/15917510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.6.2172-2179.2005
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