TGF-beta1 Does Not Induce Senescence of Multipotent Mesenchymal Stromal Cells and Has Similar Effects in Early and Late Passages

Transforming growth factor-beta 1 (TGF-β1) stimulates a broad range of effects which are cell type dependent, and it has been suggested to induce cellular senescence. On the other hand, long-term culture of multipotent mesenchymal stromal cells (MSCs) has a major impact on their cellular physiology...

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Autors principals: Walenda, Gudrun, Abnaof, Khalid, Joussen, Sylvia, Meurer, Steffen, Smeets, Hubert, Rath, Björn, Hoffmann, Kurt, Fröhlich, Holger, Zenke, Martin, Weiskirchen, Ralf, Wagner, Wolfgang
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798389/
https://ncbi.nlm.nih.gov/pubmed/24147049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077656
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