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Usage of Mitogen-Activated Protein Kinase Small Molecule Inhibitors: More Than Just Inhibition!

We have identified a phenomenon occurring in the usage of proposed “specific” Mitogen-activated protein kinase (MAPK) inhibitors. We found that especially inhibitors of p38 potentiate the activation of other MAPKs in various cell types. This finding will have tremendous impact on the interpretation...

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Detalles Bibliográficos
Publicado en:Front Pharmacol
Main Authors: Meurer, Steffen K., Weiskirchen, Ralf
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5816342/
https://ncbi.nlm.nih.gov/pubmed/29483873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00098
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