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Usage of Mitogen-Activated Protein Kinase Small Molecule Inhibitors: More Than Just Inhibition!

We have identified a phenomenon occurring in the usage of proposed “specific” Mitogen-activated protein kinase (MAPK) inhibitors. We found that especially inhibitors of p38 potentiate the activation of other MAPKs in various cell types. This finding will have tremendous impact on the interpretation...

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Bibliografiske detaljer
Udgivet i:Front Pharmacol
Main Authors: Meurer, Steffen K., Weiskirchen, Ralf
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5816342/
https://ncbi.nlm.nih.gov/pubmed/29483873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00098
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