A gene regulation network controlled by Celf1 protein–rbpj mRNA interaction in Xenopus somite segmentation

Somite segmentation is impaired in Xenopus celf1 morphant embryos. The Celf1 RNA-binding protein targets bound mRNAs for rapid degradation, and antisense approaches demonstrated that segmentation defects in celf1 morphants were due to a derepression of rbpj mRNA. Rbpj protein is a key player of Notc...

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Bibliographic Details
Main Authors: Cibois, Marie, Gautier-Courteille, Carole, Kodjabachian, Laurent, Paillard, Luc
Format: Artigo
Language:Inglês
Published: The Company of Biologists 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3798191/
https://ncbi.nlm.nih.gov/pubmed/24167718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.20135629
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