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Inactivation of CUG-BP1/CELF1 Causes Growth, Viability, and Spermatogenesis Defects in Mice

CUG-BP1/CELF1 is a multifunctional RNA-binding protein involved in the regulation of alternative splicing and translation. To elucidate its role in mammalian development, we produced mice in which the Cugbp1 gene was inactivated by homologous recombination. These Cugbp1(−)(/)(−) mice were viable, al...

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מידע ביבליוגרפי
Main Authors: Kress, Chantal, Gautier-Courteille, Carole, Osborne, H. Beverley, Babinet, Charles, Paillard, Luc
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2007
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1800704/
https://ncbi.nlm.nih.gov/pubmed/17130239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01009-06
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