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Inactivation of CUG-BP1/CELF1 Causes Growth, Viability, and Spermatogenesis Defects in Mice

CUG-BP1/CELF1 is a multifunctional RNA-binding protein involved in the regulation of alternative splicing and translation. To elucidate its role in mammalian development, we produced mice in which the Cugbp1 gene was inactivated by homologous recombination. These Cugbp1(−)(/)(−) mice were viable, al...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kress, Chantal, Gautier-Courteille, Carole, Osborne, H. Beverley, Babinet, Charles, Paillard, Luc
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1800704/
https://ncbi.nlm.nih.gov/pubmed/17130239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01009-06
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