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A strategy to analyze the phenotypic consequences of inhibiting the association of an RNA-binding protein with a specific RNA

Targeted inactivations of RNA-binding proteins (RNA-BPs) can lead to huge phenotypical defects. These defects are due to the deregulation of certain mRNAs. However, we generally do not know, among the hundreds of mRNAs that are normally controlled by one RNA-BP, which are responsible for the observe...

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Detalhes bibliográficos
Main Authors: Cibois, Marie, Gautier-Courteille, Carole, Vallée, Audrey, Paillard, Luc
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802020/
https://ncbi.nlm.nih.gov/pubmed/19933768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1742610
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