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HLA-DM Focuses on Conformational Flexibility Around P1 Pocket to Catalyze Peptide Exchange
Peptides presented by major histocompatibility complex class II (MHCII) molecules to CD4+ T cells play a central role in the initiation of adaptive immunity. This antigen presentation process is characterized by the proteolytic cleavage of foreign and self proteins, and loading of the resultant pept...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Frontiers Media S.A.
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3797982/ https://ncbi.nlm.nih.gov/pubmed/24146666 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2013.00336 |
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