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Distinct Tryptophan Catabolism and Th17/Treg Balance in HIV Progressors and Elite Controllers
Tryptophan (Trp) catabolism into immunosuppressive kynurenine (Kyn) by indoleamine 2,3-dioxygenase (IDO) was previously linked to Th17/Treg differentiation and immune activation. Here we examined Trp catabolism and its impact on Th17/Treg balance in uninfected healthy subjects (HS) and a large cohor...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3797729/ https://ncbi.nlm.nih.gov/pubmed/24147117 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0078146 |
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