Influence of Hepatitis C Virus Sustained Virological Response on Immunosuppressive Tryptophan Catabolism in ART-Treated HIV/HCV Coinfected Patients

BACKGROUND: We previously reported an association between tryptophan (Trp) catabolism and immune dysfunction in HIV monoinfection. Coinfection with HIV is associated with more rapid evolution of hepatitis C virus (HCV)–associated liver disease despite antiretroviral therapy (ART), possibly due to im...

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Udgivet i:J Acquir Immune Defic Syndr
Main Authors: Jenabian, Mohammad-Ali, Mehraj, Vikram, Costiniuk, Cecilia T., Vyboh, Kishanda, Kema, Ido, Rollet, Kathleen, Paulino Ramirez, Robert, Klein, Marina B., Routy, Jean-Pierre
Format: Artigo
Sprog:Inglês
Udgivet: JAIDS Journal of Acquired Immune Deficiency Syndromes 2016
Fag:
Basic and Translational Science
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770371/
https://ncbi.nlm.nih.gov/pubmed/26436613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0000000000000859
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