A 26-gene hypoxia signature predicts benefit from hypoxia-modifying therapy in laryngeal cancer but not bladder cancer

PURPOSE: In head and neck and bladder cancer tumor hypoxia is associated with a poor prognosis, hypoxia modification improves outcome and hypoxic status predicts benefit from treatment. Yet, there is no universal measure of clinical hypoxia. The aim of this study was to investigate whether a 26-gene...

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Hauptverfasser: Eustace, Amanda, Mani, Navin, Span, Paul N, Irlam, Joely J, Taylor, Janet, Betts, Guy NJ, Denley, Helen, Miller, Crispin J, Homer, Jarrod J, Rojas, Ana M, Hoskin, Peter J, Buffa, Francesca M, Harris, Adrian L, Kaanders, Johannes HAM, West, Catharine ML
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3797516/
https://ncbi.nlm.nih.gov/pubmed/23820108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-0542
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