A 26-gene hypoxia signature predicts benefit from hypoxia-modifying therapy in laryngeal cancer but not bladder cancer

PURPOSE: In head and neck and bladder cancer tumor hypoxia is associated with a poor prognosis, hypoxia modification improves outcome and hypoxic status predicts benefit from treatment. Yet, there is no universal measure of clinical hypoxia. The aim of this study was to investigate whether a 26-gene...

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Bibliografische gegevens
Hoofdauteurs: Eustace, Amanda, Mani, Navin, Span, Paul N, Irlam, Joely J, Taylor, Janet, Betts, Guy NJ, Denley, Helen, Miller, Crispin J, Homer, Jarrod J, Rojas, Ana M, Hoskin, Peter J, Buffa, Francesca M, Harris, Adrian L, Kaanders, Johannes HAM, West, Catharine ML
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3797516/
https://ncbi.nlm.nih.gov/pubmed/23820108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-0542
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