Prefrontal Cortical Dysfunction After Overexpression of Histone Deacetylase 1

BACKGROUND: Postmortem brain studies have shown that HDAC1—a lysine deacetylase with broad activity against histones and nonhistone proteins—is frequently expressed at increased levels in prefrontal cortex (PFC) of subjects diagnosed with schizophrenia and related disease. However, it remains unclea...

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Autors principals: Jakovcevski, Mira, Bharadwaj, Rahul, Straubhaar, Juerg, Gao, Guangping, Gavin, David P., Jakovcevski, Igor, Mitchell, Amanda C., Akbarian, Schahram
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3797203/
https://ncbi.nlm.nih.gov/pubmed/23664640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2013.03.020
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