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Maternal immune activation alters behavior in adult offspring, with subtle changes in the cortical transcriptome and epigenome
Maternal immune activation during prenatal development, including treatment with the viral RNA mimic, polyriboinosinic-polyribocytidilic acid (poly IC), serves as a widely used animal model to induce behavioral deficits reminiscent of schizophrenia and related disease. Here, we report that massive c...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3568668/ https://ncbi.nlm.nih.gov/pubmed/22804924 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.schres.2012.06.037 |
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