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Setdb1 Histone Methyltransferase Regulates Mood-Related Behaviors and Expression of the NMDA Receptor Subunit NR2B

Histone methyltransferases specific for the histone H3-lysine 9 residue, including Setdb1 (Set domain, bifurcated 1)/Eset/Kmt1e are associated with repressive chromatin remodeling and expressed in adult brain, but potential effects on neuronal function and behavior remain unexplored. Here, we report...

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Detalhes bibliográficos
Main Authors: Jiang, Yan, Jakovcevski, Mira, Bharadwaj, Rahul, Connor, Caroline, Schroeder, Frederick A., Lin, Cong L., Straubhaar, Juerg, Martin, Gilles, Akbarian, Schahram
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2893142/
https://ncbi.nlm.nih.gov/pubmed/20505083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1314-10.2010
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