Pax6 Downregulation Mediates Abnormal Lineage Commitment of the Ocular Surface Epithelium in Aqueous-Deficient Dry Eye Disease

Keratinizing squamous metaplasia (SQM) of the ocular surface is a blinding consequence of systemic autoimmune disease and there is no cure. Ocular SQM is traditionally viewed as an adaptive tissue response during chronic keratoconjunctivitis sicca (KCS) that provokes pathological keratinization of t...

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Hlavní autoři: Chen, Ying Ting, Chen, Feeling Y. T., Vijmasi, Trinka, Stephens, Denise N., Gallup, Marianne, McNamara, Nancy A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3797128/
https://ncbi.nlm.nih.gov/pubmed/24143217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077286
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