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Topical Administration of Lacritin Is a Novel Therapy for Aqueous-Deficient Dry Eye Disease

PURPOSE. Lacritin is a tear glycoprotein with prosecretory, prosurvival, and mitogenic properties. We examined lacritin levels in the tears of Sjögren's syndrome (SS) patients and explored the therapeutic potential of topical lacritin for the treatment of keratoconjunctivitis sicca. METHODS. Te...

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Autores principales: Vijmasi, Trinka, Chen, Feeling Y. T., Balasubbu, Suganthalakshmi, Gallup, Marianne, McKown, Robert L., Laurie, Gordon W., McNamara, Nancy A.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Association for Research in Vision and Ophthalmology 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4148924/
https://ncbi.nlm.nih.gov/pubmed/25034600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.14-13924
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