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ISG15 Regulates Peritoneal Macrophages Functionality against Viral Infection
Upon viral infection, the production of type I interferon (IFN) and the subsequent upregulation of IFN stimulated genes (ISGs) generate an antiviral state with an important role in the activation of innate and adaptive host immune responses. The ubiquitin-like protein (UBL) ISG15 is a critical IFN-i...
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Hauptverfasser: | , , , , , , , , , |
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Format: | Artigo |
Sprache: | Inglês |
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Public Library of Science
2013
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3796851/ https://ncbi.nlm.nih.gov/pubmed/24137104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003632 |
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