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Vaccinia Virus E3 Protein Prevents the Antiviral Action of ISG15
The ubiquitin-like modifier ISG15 is one of the most predominant proteins induced by type I interferons (IFN). In this study, murine embryo fibroblast (MEFs) and mice lacking the gene were used to demonstrate a novel role of ISG15 as a host defense molecule against vaccinia virus (VACV) infection. I...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2434199/ https://ncbi.nlm.nih.gov/pubmed/18604270 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000096 |
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