ISG15 Regulates Peritoneal Macrophages Functionality against Viral Infection

Upon viral infection, the production of type I interferon (IFN) and the subsequent upregulation of IFN stimulated genes (ISGs) generate an antiviral state with an important role in the activation of innate and adaptive host immune responses. The ubiquitin-like protein (UBL) ISG15 is a critical IFN-i...

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Detalhes bibliográficos
Main Authors: Yángüez, Emilio, García-Culebras, Alicia, Frau, Aldo, Llompart, Catalina, Knobeloch, Klaus-Peter, Gutierrez-Erlandsson, Sylvia, García-Sastre, Adolfo, Esteban, Mariano, Nieto, Amelia, Guerra, Susana
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3796851/
https://ncbi.nlm.nih.gov/pubmed/24137104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003632
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