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The ESX-3 Secretion System Is Necessary for Iron and Zinc Homeostasis in Mycobacterium tuberculosis

ESX-3 is one of the five type VII secretion systems encoded by the Mycobacterium tuberculosis genome. We recently showed the essentiality of ESX-3 for M. tuberculosis viability and proposed its involvement in iron and zinc metabolism. In this study we confirmed the role of ESX-3 in iron uptake and i...

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Detalhes bibliográficos
Main Authors: Serafini, Agnese, Pisu, Davide, Palù, Giorgio, Rodriguez, G. Marcela, Manganelli, Riccardo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3796483/
https://ncbi.nlm.nih.gov/pubmed/24155985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0078351
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