Niclosamide overcomes acquired resistance to erlotinib through suppression of STAT3 in non-small cell lung cancer

The emergence of resistance to epidermal growth factor receptor (EGFR) inhibitor therapy is a major clinical problem for patients with non-small cell lung cancer (NSCLC). The mechanisms underlying tumor resistance to inhibitors of the kinase activity of EGFR are not fully understood. Here we found t...

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Main Authors: Li, Rui, Hu, Zhongliang, Sun, Shi-Yong, Chen, Zhuo G., Owonikoko, Taofeek K., Sica, Gabriel L., Ramalingam, Suresh S., Curran, Walter J., Khuri, Fadlo R., Deng, Xingming
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795834/
https://ncbi.nlm.nih.gov/pubmed/23894143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-13-0095
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