Elevated expression of eukaryotic translation initiation factor 4E is associated with proliferation, invasion and acquired resistance to erlotinib in lung cancer

Eukaryotic translation initiation factor 4E (eIF4E) is the rate-limiting factor for cap-dependent translation initiation, which is known to regulate oncogenesis. Elevated eIF4E and its negative impact on prognosis in human non-small cell lung cancer (NSCLC) have been reported previously. However, it...

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Detalhes bibliográficos
Main Authors: Li, Yikun, Fan, Songqing, Koo, Junghui, Yue, Ping, Chen, Zhuo (Georgia), Owonikoko, Taofeek K., Ramalingam, Suresh S., Khuri, Fadlo R., Sun, Shi-Yong
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679095/
https://ncbi.nlm.nih.gov/pubmed/22236867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.18923
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