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Mathematical Modeling of the Role of Mitochondrial Fusion and Fission in Mitochondrial DNA Maintenance

Accumulation of mitochondrial DNA (mtDNA) mutations has been implicated in a wide range of human pathologies, including neurodegenerative diseases, sarcopenia, and the aging process itself. In cells, mtDNA molecules are constantly turned over (i.e. replicated and degraded) and are also exchanged amo...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Tam, Zhi Yang, Gruber, Jan, Halliwell, Barry, Gunawan, Rudiyanto
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795767/
https://ncbi.nlm.nih.gov/pubmed/24146842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076230
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