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Mathematical Modeling of the Role of Mitochondrial Fusion and Fission in Mitochondrial DNA Maintenance

Accumulation of mitochondrial DNA (mtDNA) mutations has been implicated in a wide range of human pathologies, including neurodegenerative diseases, sarcopenia, and the aging process itself. In cells, mtDNA molecules are constantly turned over (i.e. replicated and degraded) and are also exchanged amo...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Tam, Zhi Yang, Gruber, Jan, Halliwell, Barry, Gunawan, Rudiyanto
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795767/
https://ncbi.nlm.nih.gov/pubmed/24146842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076230
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