Tissue-specific dysregulation of hexose-6-phosphate dehydrogenase and glucose-6-phosphate transporter production in db/db mice as a model of type 2 diabetes

AIMS/HYPOTHESIS: Tissue-specific amplification of glucocorticoid action through 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) affects the development of the metabolic syndrome. Hexose-6-phosphate dehydrogenase (H6PDH) mediates intracellular NADPH availability for 11β-HSD1 and depends on the glu...

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Main Authors: Wang, Y., Nakagawa, Y., Liu, L., Wang, W., Ren, X., Anghel, A., Lutfy, K., Friedman, T. C., Liu, Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795617/
https://ncbi.nlm.nih.gov/pubmed/21052977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-010-1956-9
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