Formulations for Intranasal Delivery of Pharmacological Agents to Combat Brain Disease: A New Opportunity to Tackle GBM?

Despite recent advances in tumor imaging and chemoradiotherapy, the median overall survival of patients diagnosed with glioblastoma multiforme does not exceed 15 months. Infiltration of glioma cells into the brain parenchyma, and the blood-brain barrier are important hurdles to further increase the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: van Woensel, Matthias, Wauthoz, Nathalie, Rosière, Rémi, Amighi, Karim, Mathieu, Véronique, Lefranc, Florence, van Gool, Stefaan W., de Vleeschouwer, Steven
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2013
Schlagworte:
Review
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795377/
https://ncbi.nlm.nih.gov/pubmed/24202332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers5031020
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