A Brain-specific Grb2-associated Regulator of Extracellular Signal-regulated Kinase (Erk)/Mitogen-activated Protein Kinase (MAPK) (GAREM) Subtype, GAREM2, Contributes to Neurite Outgrowth of Neuroblastoma Cells by Regulating Erk Signaling

Grb2-associated regulator of Erk/MAPK1 (GAREM) is an adaptor molecule in the EGF-mediated signaling pathway. GAREM is expressed ubiquitously in human organs and cultured cells. Two GAREM homologues are encoded by the human genome. Therefore, previously identified GAREM is named GAREM1. Here we chara...

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Détails bibliographiques
Auteurs principaux: Taniguchi, Tomonori, Tanaka, Shigeru, Ishii, Ayumi, Watanabe, Miyuki, Fujitani, Noriko, Sugeo, Ayusa, Gotoh, Shuhei, Ohta, Takeshi, Hiyoshi, Mineyoshi, Matsuzaki, Hideki, Sakai, Norio, Konishi, Hiroaki
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2013
Sujets:
Cell Biology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795291/
https://ncbi.nlm.nih.gov/pubmed/24003223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.492520
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