A Brain-specific Grb2-associated Regulator of Extracellular Signal-regulated Kinase (Erk)/Mitogen-activated Protein Kinase (MAPK) (GAREM) Subtype, GAREM2, Contributes to Neurite Outgrowth of Neuroblastoma Cells by Regulating Erk Signaling

Grb2-associated regulator of Erk/MAPK1 (GAREM) is an adaptor molecule in the EGF-mediated signaling pathway. GAREM is expressed ubiquitously in human organs and cultured cells. Two GAREM homologues are encoded by the human genome. Therefore, previously identified GAREM is named GAREM1. Here we chara...

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Autores principales: Taniguchi, Tomonori, Tanaka, Shigeru, Ishii, Ayumi, Watanabe, Miyuki, Fujitani, Noriko, Sugeo, Ayusa, Gotoh, Shuhei, Ohta, Takeshi, Hiyoshi, Mineyoshi, Matsuzaki, Hideki, Sakai, Norio, Konishi, Hiroaki
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2013
Materias:
Cell Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795291/
https://ncbi.nlm.nih.gov/pubmed/24003223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.492520
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