A Brain-specific Grb2-associated Regulator of Extracellular Signal-regulated Kinase (Erk)/Mitogen-activated Protein Kinase (MAPK) (GAREM) Subtype, GAREM2, Contributes to Neurite Outgrowth of Neuroblastoma Cells by Regulating Erk Signaling

Grb2-associated regulator of Erk/MAPK1 (GAREM) is an adaptor molecule in the EGF-mediated signaling pathway. GAREM is expressed ubiquitously in human organs and cultured cells. Two GAREM homologues are encoded by the human genome. Therefore, previously identified GAREM is named GAREM1. Here we chara...

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Detalhes bibliográficos
Principais autores: Taniguchi, Tomonori, Tanaka, Shigeru, Ishii, Ayumi, Watanabe, Miyuki, Fujitani, Noriko, Sugeo, Ayusa, Gotoh, Shuhei, Ohta, Takeshi, Hiyoshi, Mineyoshi, Matsuzaki, Hideki, Sakai, Norio, Konishi, Hiroaki
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795291/
https://ncbi.nlm.nih.gov/pubmed/24003223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.492520
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