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Noncanonical Transforming Growth Factor β (TGFβ) Signaling in Cranial Neural Crest Cells Causes Tongue Muscle Developmental Defects

Microglossia is a congenital birth defect in humans and adversely impacts quality of life. In vertebrates, tongue muscle derives from the cranial mesoderm, whereas tendons and connective tissues in the craniofacial region originate from cranial neural crest (CNC) cells. Loss of transforming growth f...

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Autori principali: Iwata, Jun-ichi, Suzuki, Akiko, Pelikan, Richard C., Ho, Thach-Vu, Chai, Yang
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795273/
https://ncbi.nlm.nih.gov/pubmed/23950180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.493551
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