Procoagulant Platelets Form an α-Granule Protein-covered “Cap” on Their Surface That Promotes Their Attachment to Aggregates

Strongly activated “coated” platelets are characterized by increased phosphatidylserine (PS) surface expression, α-granule protein retention, and lack of active integrin α(IIb)β(3). To study how they are incorporated into thrombi despite a lack of free activated integrin, we investigated the structu...

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Autori principali: Abaeva, Anastasia A., Canault, Matthias, Kotova, Yana N., Obydennyy, Sergey I., Yakimenko, Alena O., Podoplelova, Nadezhda A., Kolyadko, Vladimir N., Chambost, Herve, Mazurov, Aleksei V., Ataullakhanov, Fazoil I., Nurden, Alan T., Alessi, Marie-Christine, Panteleev, Mikhail A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2013
Soggetti:
Cell Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795260/
https://ncbi.nlm.nih.gov/pubmed/23995838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.474163
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