Procoagulant Platelets Form an α-Granule Protein-covered “Cap” on Their Surface That Promotes Their Attachment to Aggregates

Strongly activated “coated” platelets are characterized by increased phosphatidylserine (PS) surface expression, α-granule protein retention, and lack of active integrin α(IIb)β(3). To study how they are incorporated into thrombi despite a lack of free activated integrin, we investigated the structu...

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Main Authors: Abaeva, Anastasia A., Canault, Matthias, Kotova, Yana N., Obydennyy, Sergey I., Yakimenko, Alena O., Podoplelova, Nadezhda A., Kolyadko, Vladimir N., Chambost, Herve, Mazurov, Aleksei V., Ataullakhanov, Fazoil I., Nurden, Alan T., Alessi, Marie-Christine, Panteleev, Mikhail A.
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2013
主題:
Cell Biology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795260/
https://ncbi.nlm.nih.gov/pubmed/23995838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.474163
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