Type I Interferon Upregulates Bak and Contributes to T Cell Loss during Human Immunodeficiency Virus (HIV) Infection

The role of Type I interferon (IFN) during pathogenic HIV and SIV infections remains unclear, with conflicting observations suggesting protective versus immunopathological effects. We therefore examined the effect of IFNα/β on T cell death and viremia in HIV infection. Ex vivo analysis of eight pro-...

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Bibliografski detalji
Glavni autori: Fraietta, Joseph A., Mueller, Yvonne M., Yang, Guibin, Boesteanu, Alina C., Gracias, Donald T., Do, Duc H., Hope, Jennifer L., Kathuria, Noshin, McGettigan, Shannon E., Lewis, Mark G., Giavedoni, Luis D., Jacobson, Jeffrey M., Katsikis, Peter D.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795023/
https://ncbi.nlm.nih.gov/pubmed/24130482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003658
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