Human Cytomegalovirus Latency-Associated Proteins Elicit Immune-Suppressive IL-10 Producing CD4(+) T Cells

Human cytomegalovirus (HCMV) is a widely prevalent human herpesvirus, which, after primary infection, persists in the host for life. In healthy individuals, the virus is well controlled by the HCMV-specific T cell response. A key feature of this persistence, in the face of a normally robust host imm...

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Détails bibliographiques
Auteurs principaux: Mason, Gavin M., Jackson, Sarah, Okecha, Georgina, Poole, Emma, Sissons, J. G. Patrick, Sinclair, John, Wills, Mark R.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795018/
https://ncbi.nlm.nih.gov/pubmed/24130479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003635
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