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Human cytomegalovirus latency alters the cellular secretome, inducing cluster of differentiation (CD)4(+) T-cell migration and suppression of effector function
After primary infection, human cytomegalovirus (HCMV) persists as a life-long latent infection, with host immunosuppression often resulting in clinical reactivation. During lytic infection, major changes in the expression of secreted cellular proteins (the secretome) occur that have profound effects...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3437838/ https://ncbi.nlm.nih.gov/pubmed/22826250 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1204836109 |
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