Integrated analysis of genome-wide DNA methylation and gene expression profiles in molecular subtypes of breast cancer

Aberrant DNA methylation of CpG islands, CpG island shores and first exons is known to play a key role in the altered gene expression patterns in all human cancers. To date, a systematic study on the effect of DNA methylation on gene expression using high resolution data has not been reported. In th...

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Bibliographische Detailangaben
Hauptverfasser: Rhee, Je-Keun, Kim, Kwangsoo, Chae, Heejoon, Evans, Jared, Yan, Pearlly, Zhang, Byoung-Tak, Gray, Joe, Spellman, Paul, Huang, Tim H.-M., Nephew, Kenneth P., Kim, Sun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2013
Schlagworte:
Computational Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3794600/
https://ncbi.nlm.nih.gov/pubmed/23887935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt643
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