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Modulation of base excision repair of 8-oxoguanine by the nucleotide sequence
8-Oxoguanine (8-oxoG) is a major product of oxidative DNA damage, which induces replication errors and interferes with transcription. By varying the position of single 8-oxoG in a functional gene and manipulating the nucleotide sequence surrounding the lesion, we found that the degree of transcripti...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3794583/ https://ncbi.nlm.nih.gov/pubmed/23863843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt620 |
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