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Controlling the stoichiometry and strand polarity of a tetramolecular G-quadruplex structure by using a DNA origami frame

Guanine-rich oligonucleotides often show a strong tendency to form supramolecular architecture, the so-called G-quadruplex structure. Because of the biological significance, it is now considered to be one of the most important conformations of DNA. Here, we describe the direct visualization and sing...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Rajendran, Arivazhagan, Endo, Masayuki, Hidaka, Kumi, Lan Thao Tran, Phong, Mergny, Jean-Louis, Sugiyama, Hiroshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3794576/
https://ncbi.nlm.nih.gov/pubmed/23863846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt592
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