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Controlling the stoichiometry and strand polarity of a tetramolecular G-quadruplex structure by using a DNA origami frame

Guanine-rich oligonucleotides often show a strong tendency to form supramolecular architecture, the so-called G-quadruplex structure. Because of the biological significance, it is now considered to be one of the most important conformations of DNA. Here, we describe the direct visualization and sing...

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Autors principals: Rajendran, Arivazhagan, Endo, Masayuki, Hidaka, Kumi, Lan Thao Tran, Phong, Mergny, Jean-Louis, Sugiyama, Hiroshi
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3794576/
https://ncbi.nlm.nih.gov/pubmed/23863846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt592
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