The transporter ABCB7 is a mediator of the phenotype of acquired refractory anemia with ring sideroblasts

Refractory anemia with ring sideroblasts (RARS) is characterized by mitochondrial ferritin (FTMT) accumulation and markedly suppressed expression of the iron transporter ABCB7. To test the hypothesis that ABCB7 is a key mediator of ineffective erythropoiesis of RARS, we modulated its expression in h...

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Main Authors: Nikpour, Maryam, Scharenberg, Christian, Liu, Anquan, Conte, Simona, Karimi, Mohsen, Mortera-Blanco, Teresa, Giai, Valentina, Fernandez-Mercado, Marta, Papaemmanuil, Elli, Högstrand, Kari, Jansson, Monika, Vedin, Inger, Wainscoat, James Stephen, Campbell, Peter, Cazzola, Mario, Boultwood, Jacqueline, Grandien, Alf, Hellström-Lindberg, Eva
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3794445/
https://ncbi.nlm.nih.gov/pubmed/23070040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2012.298
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