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Crystal Structure of a Bioactive Pactamycin Analog Bound to the 30S Ribosomal Subunit()
Biosynthetically and chemically derived analogs of the antibiotic pactamycin and de-6-methylsalicylyl (MSA)-pactamycin have attracted recent interest as potential antiprotozoal and antitumor drugs. Here, we report a 3.1-Å crystal structure of de-6-MSA-pactamycin bound to its target site on the Therm...
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| Main Authors: | , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Elsevier
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3794158/ https://ncbi.nlm.nih.gov/pubmed/23702293 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2013.05.004 |
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