Crystal Structure of a Bioactive Pactamycin Analog Bound to the 30S Ribosomal Subunit()

Biosynthetically and chemically derived analogs of the antibiotic pactamycin and de-6-methylsalicylyl (MSA)-pactamycin have attracted recent interest as potential antiprotozoal and antitumor drugs. Here, we report a 3.1-Å crystal structure of de-6-MSA-pactamycin bound to its target site on the Therm...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Tourigny, David S., Fernández, Israel S., Kelley, Ann C., Vakiti, Ramkrishna Reddy, Chattopadhyay, Amit Kumar, Dorich, Stéphane, Hanessian, Stephen, Ramakrishnan, V.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2013
Assuntos:
Brevia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3794158/
https://ncbi.nlm.nih.gov/pubmed/23702293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2013.05.004
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados