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Topical Application of PPADS Inhibits Complement Activation and Choroidal Neovascularization in a Model of Age-Related Macular Degeneration

Age-related macular degeneration (AMD) is the most common cause of blindness among the elderly. AMD patients have elevated levels of membrane attack complex (MAC) in their choroidal blood vessels and retinal pigment epithelium (RPE). MAC forms pores in cell membranes. Low levels of MAC result in an...

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Détails bibliographiques
Auteurs principaux: Birke, Kerstin, Lipo, Erion, Birke, Marco T., Kumar-Singh, Rajendra
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3793916/
https://ncbi.nlm.nih.gov/pubmed/24130789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076766
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