Tsukushi Functions as an Organizer Inducer by Inhibition of BMP Activity in Cooperation with Chordin

During chick gastrulation, inhibition of BMP signaling is required for primitive streak formation and induction of Hensen’s node. We have identified a unique secreted protein, Tsukushi (TSK), which belongs to the Small Leucine-Rich Proteoglycan (SLRP) family and is expressed in the primitive streak...

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Bibliographic Details
Main Authors: Ohta, Kunimasa, Lupo, Giuseppe, Kuriyama, Sei, Keynes, Roger, Holt, Christine E., Harris, William A., Tanaka, Hideaki, Ohnuma, Shin-ichi
Format: Artigo
Language:Inglês
Published: 2004
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3793302/
https://ncbi.nlm.nih.gov/pubmed/15363410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2004.08.014
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