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Tsukushi functions as a Wnt signaling inhibitor by competing with Wnt2b for binding to transmembrane protein Frizzled4
The Wnt signaling pathway is essential for the development of diverse tissues during embryogenesis. Signal transduction is activated by the binding of Wnt proteins to the type I receptor low-density lipoprotein receptor–related protein 5/6 and the seven-pass transmembrane protein Frizzled (Fzd), whi...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3169124/ https://ncbi.nlm.nih.gov/pubmed/21856951 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1100513108 |
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