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Tsukushi functions as a Wnt signaling inhibitor by competing with Wnt2b for binding to transmembrane protein Frizzled4

The Wnt signaling pathway is essential for the development of diverse tissues during embryogenesis. Signal transduction is activated by the binding of Wnt proteins to the type I receptor low-density lipoprotein receptor–related protein 5/6 and the seven-pass transmembrane protein Frizzled (Fzd), whi...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Ohta, Kunimasa, Ito, Ayako, Kuriyama, Sei, Lupo, Giuseppe, Kosaka, Mitsuko, Ohnuma, Shin-ichi, Nakagawa, Shinichi, Tanaka, Hideaki
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3169124/
https://ncbi.nlm.nih.gov/pubmed/21856951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1100513108
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