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Mechanisms of Drug Induced Liver Injury

Drug induced liver injury (DILI) represents a broad spectrum of liver manifestations. However, the most common manifestation is hepatocyte death following drug intake. DILI can be predictable and dose dependent with notable example of acetaminophen toxicity. Idiosyncratic DILI occurs in an unpredict...

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Detalles Bibliográficos
Main Authors: Yuan, Liyun, Kaplowitz, Neil
Formato: Artigo
Idioma:Inglês
Publicado: 2013
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3793205/
https://ncbi.nlm.nih.gov/pubmed/24099014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cld.2013.07.002
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