Activation of antigen-presenting cells by microbial products breaks self tolerance and induces autoimmune disease

We describe the generation of mice that express a transgenic T cell receptor (TCR) (5B6) specific for the encephalitogenic myelin proteolipid protein (PLP) peptide 139–151, on the experimental autoimmune encephalomyelitis–resistant (EAE-resistant) B10.S background. Despite harboring a high frequency...

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Pubblicato in:	J Clin Invest
Autori principali:	Waldner, Hanspeter, Collins, Mary, Kuchroo, Vijay K.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 2004
Soggetti:	Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC379316/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15057305/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI19388
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