Activation of antigen-presenting cells by microbial products breaks self tolerance and induces autoimmune disease

We describe the generation of mice that express a transgenic T cell receptor (TCR) (5B6) specific for the encephalitogenic myelin proteolipid protein (PLP) peptide 139–151, on the experimental autoimmune encephalomyelitis–resistant (EAE-resistant) B10.S background. Despite harboring a high frequency...

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Hlavní autoři: Waldner, Hanspeter, Collins, Mary, Kuchroo, Vijay K.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2004
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC379316/
https://ncbi.nlm.nih.gov/pubmed/15057305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200419388
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