Activation of antigen-presenting cells by microbial products breaks self tolerance and induces autoimmune disease

We describe the generation of mice that express a transgenic T cell receptor (TCR) (5B6) specific for the encephalitogenic myelin proteolipid protein (PLP) peptide 139–151, on the experimental autoimmune encephalomyelitis–resistant (EAE-resistant) B10.S background. Despite harboring a high frequency...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Waldner, Hanspeter, Collins, Mary, Kuchroo, Vijay K.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 2004
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC379316/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15057305/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI19388
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